The accuracy of the EDDP Urine Drug Test was
evaluated in comparison to GC/MS method and commercial kits at a cut-off of 100
ng/mL. EDDP Ninety nine (99) specimens which composed of forty four (44)
positive samples and forty five (45) negative samples were evaluated in this
study. Methadone is a synthetic opiate agonist that is often used in
detoxification programs as an oral substitute for heroin or other morphine-like
drugs to suppress withdrawal symptoms and/or to maintain chronic replacing
heroin addicts. The benefit of measuring EDDP instead of methadone is
that individuals in methadone programs sometimes divert their methadone into
the illicit drug market and then spike their urine sample with a small quantity
of methadone to cover the diversion. Their urine sample may test positive
for methadone but would not test positive for EDDP, since the drug was not
ingested and therefore never metabolized. EDDP urine drug test is intended
for healthcare professional use and provides preliminary screening results. It
is recommended that a more specific chemical method (i.e. GC/MS) be used
in order to obtain a confirmed analytical result